Berberine vs Ozempic: What the Science Shows
Berberine is a plant alkaloid studied for blood sugar support, while Ozempic is a prescription GLP-1 agonist for diabetes and weight loss. Evidence differs substantially in scale and mechanism.
Supplement Articles
19 evidence-led guides · Bilingual (EN / 中文) · AI-friendly markdown alternates
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Comparisons (1)
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Best Supplements for Hot Flashes: Evidence-Ranked Options
Hot flashes affect millions during menopause. We review the most studied supplements for hot flashes—from black cohosh to soy isoflavones—with dosing and safety details.
Safety & deficiency (2)
Methylene Blue and SSRIs: Serotonin Syndrome Risk
Methylene blue can dangerously increase serotonin levels when combined with SSRIs, potentially triggering serotonin syndrome. Understanding this interaction is critical for safe supplement use.
USP Grade vs Industrial Methylene Blue: Why Purity Matters
USP grade methylene blue meets strict pharmaceutical standards for purity and identity, while industrial grades may contain contaminants. Understanding the difference is critical for supplement safety
Guides & how-to (15)
Andrew Huberman's Supplement Stack: Sleep, Focus & Performance
Neuroscientist Andrew Huberman's science-backed supplement protocol includes magnesium, omega-3s, vitamin D, and other compounds targeting sleep quality, cognitive performance, and stress resilience.
Bryan Johnson Blueprint Supplement Stack: Full List & Evidence
Bryan Johnson's Blueprint stack is a longevity-focused supplement regimen backed by research on aging and healthspan. This guide reviews each ingredient, doses, and what science currently says about t
Colostrum Supplement Benefits Evidence and Hype Explained
Colostrum is a nutrient-rich milk secretion with immune proteins and growth factors. This guide reviews the evidence on absorption, safety, and which claims hold up.
Cortisol Support Supplements for Women Over 40
Cortisol supplements marketed to women over 40 often contain adaptogens like ashwagandha and rhodiola. Evidence shows some may modestly support stress resilience, though clinical benefits are small an
David Sinclair Supplement Stack: What He Takes & the Evidence
Harvard aging researcher David Sinclair is known for taking a specific supplement regimen focused on longevity. Learn which supplements he uses, the science behind them, and whether they're right for
Eriomin Eriocitrin: Lemon Flavonoid for Metabolic Health
Eriomin is a patented form of eriocitrin, a citrus flavonoid studied for blood sugar regulation and metabolic support. Evidence is preliminary but suggests potential benefits for glucose control and a
HRT Alternatives: Supplement Evidence for Hormone Support
Explore evidence-backed supplements studied for hormone support, including black cohosh, red clover, and soy isoflavones, with data on efficacy, safety, and who they may benefit.
Joe Rogan Supplement Stack: What He Takes and What Science Says
Joe Rogan has publicly shared his daily supplement regimen for years. We review his stack with evidence on each ingredient's purported benefits and limitations.
Methylene Blue Benefits: Cognitive, Mitochondrial & Antimicrobial Evidence
Methylene blue is a synthetic compound studied for supporting mitochondrial function, cognitive performance, and antimicrobial activity. Evidence is emerging but preliminary for most applications.
Methylene Blue Dosing Guide: Safe Cognitive Doses
Methylene blue is a redox-active compound studied for cognitive support, with typical dosing ranging from 5–20 mg daily. This guide covers evidence-based dosing, bioavailability factors, and safety co
Nature's Ozempic Supplements: What Actually Works for Weight and Metabolism
Explore science-backed natural supplements marketed as GLP-1 alternatives, including berberine, chromium, and fiber compounds. Learn which have credible evidence and how they compare to prescription m
Nicotinamide Riboside (NR): Benefits, Dosage & Effects
Nicotinamide riboside is a precursor to NAD+, a coenzyme critical for cellular energy and aging-related processes. This guide covers its mechanism, evidence, dosing, and how it compares to similar com
Perimenopause Supplements: Evidence-Based Symptom Relief
Perimenopause supplements can help manage hot flashes, mood changes, and sleep disruption during the transition to menopause. This guide reviews evidence for the most studied options and how to use th
Peter Attia Supplement List: Evidence-Based Longevity Stack
Explore the science-backed supplements recommended by longevity expert Peter Attia, including magnesium, omega-3s, vitamin D, and others designed to support healthy aging.
Vitamin D & Magnesium for Perimenopause Sleep
Vitamin D and magnesium address common sleep disruptions during perimenopause by supporting hormone balance and nervous system calm. Evidence suggests both may improve sleep quality when deficiency is